Portal Vein Thrombosis: The Overlooked Association between Pancreatic Cancer and PVT

Abstract :

Portal vein thrombosis (PVT) is a complication of prothrombic disorders, liver cirrhosis and malignancies.
Pancreatic malignancy, specifically, is notorious for this complication because it up regulates tissue factor production, which activates the extrinsic coagulation cascade, thus inducing a hypercoagulable state. In this state, the body is susceptible to thrombus formation, resulting in venous thromboembolism (VTE) or PVT. Thus, considering a pancreatic malignancy as a top differential for PVT must be emphasized.

Author Name : Yasra Badi, Dr. Nabil Badro & Shreena Dhawan

DOI: https://doi.org/10.5281/zenodo.291378

Keywords: Pancreatic Cancer, Portal Vein Thrombosis, Hypercoagulability, Malignancy, Prothrombic Disorders.