Synthesis, Characterization, and Biological Activity of Some Metal Complexes derived from Isatin.

Author(s) Name

Ream Nafea,  Abeer A. Faheim,  Zeinab A. El-Shafiey, EmanHelmy

Abstract

Condensation of isatin with 2-amino-5-chloropyridene readily gives rise to Schiff-base ligand, L. Its reactions with Co(II) and Cd(II) ions give a series of new complexes. All the synthesized metal complexes were found to be coloured, nonhygroscobic in nature, stable in air. The metal complexes structurally characterized with spectroscopic methods, magnetic, and conductivity measurements. The data showed that the Schiff base ligand, L, behaves as a tridentate via nitrogen atom of azomethine group, oxygen atom of isatin carbonyl and nitrogen atom of pyridine ring moiety. The results obtained from magnetic moments, electronic spectra, mass spectra and elemental analyses confirmed the octahedral geometry around the central metal ions.

Keywords: Schiff-base ligand; metal complexes; biological activity. 

Please cite this article as: Ream Nafea,  Abeer A. Faheim,  Zeinab A. El-Shafiey,EmanHelmy  (2021). Synthesis, Characterization, and Biological Activity of Some Metal Complexes derived from Isatin.  . International Journal of Recent Research and Applied Studies, 8, 3(12), 60-67.